On Determining if Tree-based Networks Contain Fixed Trees
Maria Anaya, Olga Anipchenko-Ulaj, Aisha Ashfaq, Joyce Chiu, Mahedi, Kaiser, Max Shoji Ohsawa, Megan Owen, Ella Pavlechko, Katherine St. John,, Shivam Suleria, Keith Thompson, Corrine Yap

TL;DR
This paper proves that determining whether a phylogenetic network is based on a fixed tree is NP-hard, but also fixed parameter tractable, addressing an open question in phylogenetics.
Contribution
It establishes the NP-hardness of the problem and shows it is fixed parameter tractable, advancing understanding of phylogenetic network analysis.
Findings
NP-hardness of deciding if a network is based on a fixed tree
The problem is fixed parameter tractable
Addresses an open question in phylogenetics
Abstract
We address an open question of Francis and Steel about phylogenetic networks and trees. They give a polynomial time algorithm to decide if a phylogenetic network, N, is tree-based and pose the problem: given a fixed tree T and network N, is N based on T? We show that it is NP-hard to decide, by reduction from 3-Dimensional Matching (3DM), and further, that the problem is fixed parameter tractable.
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Taxonomy
TopicsGenomics and Phylogenetic Studies · Genetic diversity and population structure · Genome Rearrangement Algorithms
