Estimation of the Accuracy of Method for Quantitative Determination of Volatile Compounds in Alcohol Products

TL;DR

This paper evaluates the precision and measurement uncertainty of a gas chromatography method for quantifying volatile compounds in alcohol products, demonstrating its reliability across various compounds and concentrations.

Contribution

It provides an empirical assessment of measurement accuracy and uncertainty for a specific gas chromatography method following ISO standards.

Findings

Measurement uncertainty ranges from 2% to 20%.

The method shows consistent precision across different compounds.

Uncertainty increases with lower concentrations.

Abstract

Results of the estimation of the precision for determination volatile compounds in alcohol-containing products by gas chromatography: acetaldehyde, methyl acetate, ethyl acetate, methanol, isopropyl alcohol, propyl alcohol, isobutyl alcohol, butyl alcohol, isoamyl alcohol are presented. To determine the accuracy, measurements were planned in accordance with ISO 5725 and held at the gas chromatograph Chromatec-Crystal 5000. Standard deviation of repeatability, intermediate precision and their limits are derived from obtained experimental data. The uncertainty of the measurements was calculated on the base of an "empirical" method. The obtained values of accuracy indicate that the developed method allows measurement uncertainty extended from 2 to 20% depending on the analyzed compound and measured concentration.