Amplifiers for the Moran Process

TL;DR

This paper introduces 'megastars', an infinite family of directed graphs that strongly amplify the Moran process, providing the first rigorous proof of such amplification and comparing it to previously proposed structures.

Contribution

The paper rigorously proves the existence of 'megastars' as strongly amplifying graphs for the Moran process, establishing their effectiveness over other known structures.

Findings

Megastars have extinction probability roughly n^{-1/2}

Superstars and metafunnels have larger extinction probabilities

Analysis of megastars is tight, with no smaller extinction probabilities possible

Abstract

The Moran process, as studied by Lieberman, Hauert and Nowak, is a randomised algorithm modelling the spread of genetic mutations in populations. The algorithm runs on an underlying graph where individuals correspond to vertices. Initially, one vertex (chosen u.a.r.) possesses a mutation, with fitness r>1. All other individuals have fitness 1. During each step of the algorithm, an individual is chosen with probability proportional to its fitness, and its state (mutant or non-mutant) is passed on to an out-neighbour which is chosen u.a.r. If the underlying graph is strongly connected then the algorithm will eventually reach fixation, in which all individuals are mutants, or extinction, in which no individuals are mutants. An infinite family of directed graphs is said to be strongly amplifying if, for every r>1, the extinction probability tends to 0 as the number of vertices increases. Lieberman et al. proposed two potentially strongly-amplifying families - superstars and metafunnels. Heuristic arguments have been published, arguing that there are infinite families of superstars that are strongly amplifying. The same has been claimed for metafunnels. In this paper, we give the first rigorous proof that there is an infinite family of directed graphs that is strongly amplifying. We call the graphs in the family "megastars". When the algorithm is run on an n-vertex graph in this family, starting with a uniformly-chosen mutant, the extinction probability is roughly $n^{-1/2}$ (up to logarithmic factors). We prove that all infinite families of superstars and metafunnels have larger extinction probabilities (as a function of n). Finally, we prove that our analysis of megastars is fairly tight - there is no infinite family of megastars such that the Moran algorithm gives a smaller extinction probability (up to logarithmic factors).