Understanding Functional Protein-Protein Interactions Of ABCB11 And ADA In Human And Mouse

TL;DR

This study investigates the quantitative protein-protein interactions of ABCB11 and ADA in humans and mice, aiming to understand regulatory factors and species-specific interaction differences.

Contribution

It provides a comparative quantitative analysis of PPIs for ABCB11 and ADA across human and mouse species, highlighting regulatory factors and interaction variations.

Findings

Quantified PPIs of ABCB11 and ADA in humans and mice.

Identified species-specific differences in protein interactions.

Analyzed factors regulating PPIs across species.

Abstract

Proteins are macromolecules which hardly act alone; they need to make interactions with some other proteins to do so. Numerous factors are there which can regulate the interactions between proteins [4]. Here in this present study we aim to understand Protein -Protein Interactions (PPIs) of two proteins ABCB11 and ADA from quantitative point of view. One of our major aims also is to study the factors that regulate the PPIs and thus to distinguish these PPIs with proper quantification across the two species Homo Sapiens and Mus Musculus respectively to know how one protein interacts with different set of proteins in different species.