Integrated Surface-enhanced Raman Spectroscopy chip based on liquid core waveguide
Chunhong Lai, Gang Chen, Li Chen, Junhui Li, Qinghao Liu, Yi Xu
TL;DR
This paper introduces an integrated SERS chip utilizing a liquid-core waveguide that achieves high Raman enhancement and excellent repeatability, enabling detailed biochemical detection.
Contribution
The work presents a novel integrated SERS chip combining liquid-core waveguide and microfluidics for improved biochemical sensing.
Findings
Raman enhancement factor of 2.5*10^5 for rhodamine 6G
High repeatability in SERS measurements
Clear molecular structure identification in DNA spectrum
Abstract
We propose an integrated surface enhanced Raman scattering (SERS) chip based on liquid-core waveguide with total reflection, through which the depression of leaky mode enable a long propagating distance. An Raman enhancement factor for rhodamine 6G of 2.5*105 is obtained, and a excellent repeatability is shown. The peaks in the SERS spectrum of DNA of silkworm clearly illustrate the information of the molecule structure. The integration of the SERS substrate, micro-fluid, and liquid-core waveguide make such a SERS chip attractive for biochemical detection with high performance.
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Taxonomy
TopicsAdvanced Biosensing Techniques and Applications · Gold and Silver Nanoparticles Synthesis and Applications · Photonic and Optical Devices