Vertical One-Dimensional Photonic Crystal Platforms for Label-Free (Bio)Sensing: Towards Drop-And- Measure Applications

TL;DR

This paper reviews all-silicon integrated optofluidic platforms utilizing vertical one-dimensional high-aspect-ratio photonic crystals, highlighting their potential for label-free biosensing and point-of-care applications.

Contribution

It introduces a fabrication approach for vertical photonic crystal platforms and discusses their application potential in flow-through biosensing and refractometry.

Findings

Potential for point-of-care biosensing applications

Compatibility with pressure-driven and capillarity-driven operations

Advantages of vertical high-aspect-ratio photonic crystals

Abstract

In this work, all-silicon, integrated optofluidic platforms, fabricated by electrochemical micromachining technology, making use of vertical, one-dimensional high-aspect- ratio photonic crystals for flow-through (bio)sensing applications are reviewed. The potential of such platforms for point-of-care applications is discussed for both pressure-driven and capillarity- driven operations with reference to refractometry and biochemical sensing.