PET-MRI: a review of challenges and solutions in the development of integrated multimodality imaging

TL;DR

This review discusses the technical challenges and solutions in developing integrated PET-MRI systems, covering detector technologies, system integration, and correction techniques for improved multimodal imaging.

Contribution

It provides a comprehensive overview of the development, technical problems, and solutions in PET-MRI integration for both preclinical and clinical applications.

Findings

Comparison of detector concepts and interference minimization techniques

Analysis of system limitations and advantages in PET-MRI integration

Discussion of attenuation correction, motion correction, and resolution recovery methods

Abstract

The integration of positron emission tomography (PET) and magnetic resonance imaging (MRI) has been an ongoing research topic for the last 20 years. This paper gives an overview of the different developments and the technical problems associated with combining PET and MRI in one system. After explaining the different detector concepts for integrating PET-MRI and minimising interference the limitations and advantages of different solutions for the detector and system are described for preclinical and clinical imaging systems. The different integrated PET-MRI systems are described in detail. Besides detector concepts and system integration the challenges and proposed solutions for attenuation correction and the potential for motion correction and resolution recovery are also discussed in this topical review.