Splicing Systems from Past to Future: Old and New Challenges

TL;DR

This survey reviews the evolution and recent advances in splicing systems, a formal model inspired by DNA recombination, highlighting ongoing challenges and future research directions.

Contribution

It provides a comprehensive overview of the development of splicing systems, emphasizing recent results and open problems in both linear and circular cases.

Findings

Recent results stimulate new research directions

Advances in linear and circular splicing systems

Identification of open challenges in the field

Abstract

A splicing system is a formal model of a recombinant behaviour of sets of double stranded DNA molecules when acted on by restriction enzymes and ligase. In this survey we will concentrate on a specific behaviour of a type of splicing systems, introduced by P\u{a}un and subsequently developed by many researchers in both linear and circular case of splicing definition. In particular, we will present recent results on this topic and how they stimulate new challenging investigations.