IR-Laser Welding and Ablation of Biotissue Stained with Metal Nanoparticles

TL;DR

This study explores laser welding and ablation of biotissue stained with metal nanoparticles using infrared laser irradiation, demonstrating significantly increased effectiveness and a novel laser point welding scheme for deep tissue layers.

Contribution

It introduces a method for laser welding and ablation of biotissue with metal nanoparticles at wavelengths far from plasmon resonances, enhancing efficiency.

Findings

Laser ablation effectiveness increased 4-5 times with metal NPs.

Successful demonstration of laser point welding for deep tissue layers.

Formation of various hybrid metal nanoparticles in liquid medium.

Abstract

In the present work we have studied the possibility of laser welding and ablation of biological tissue by the using of spherical metal nanoparticles (NPs) and infrared laser irradiation which spectrally located far from plasmon resonances. YAG:Nd laser with 1064 nm wavelength, 8 ns pulse duration, and operating in transverse electromagnetic modes TEM$_{00}$ was used for the synthesis of metal NPs. The Au,Ti Ni and Cu as well as Au-Ag and Au-Cu hybrid metal NPs were formed in the liquid medium. Effectiveness of laser ablation in the case of the biotissue sample that stained with the metal NPs was approximately on 4-5 times larger than for the native sample. Also the scheme of a laser point welding for the deep-located biotissue layer selectively stained by the metal NPs has been demonstrated.