Simulated single molecule microscopy with SMeagol
Martin Lind\'en, Vladimir \'Curi\'c, Alexis Boucharin, David, Fange, Johan Elf
TL;DR
SMeagol is a software tool that generates realistic simulated microscopy data from spatial systems biology models to aid in developing and validating analysis methods for live cell single molecule microscopy.
Contribution
The paper introduces SMeagol, a new software tool that simulates realistic microscopy data based on spatial models, enhancing validation of analysis techniques.
Findings
Provides realistic simulated microscopy data
Supports validation of analysis methods
Compatible with multiple operating systems
Abstract
SMeagol is a software tool to simulate highly realistic microscopy data based on spatial systems biology models, in order to facilitate development, validation, and optimization of advanced analysis methods for live cell single molecule microscopy data. Availability and Implementation: SMeagol runs on Matlab R2014 and later, and uses compiled binaries in C for reaction-diffusion simulations. Documentation, source code, and binaries for recent versions of Mac OS, Windows, and Ubuntu Linux can be downloaded from http://smeagol.sourceforge.net.
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