Misrepair mechanism: a mechanism essential for individual adaptation, species adaptation and species evolution

TL;DR

The paper discusses how the Misrepair mechanism is crucial not only for aging but also for individual and species adaptation, survival, and evolution by promoting diversity and resilience in changing environments.

Contribution

It introduces the role of Misrepair as a key mechanism in biological adaptation and evolution, extending its significance beyond aging to species survival and differentiation.

Findings

Misrepair enhances individual adaptation to environmental changes.

Misrepair contributes to genetic diversity within a species.

Misrepair mechanisms are vital for species evolution and survival.

Abstract

In Misrepair-accumulation theory, we have proposed a Misrepair mechanism for interpreting aging. However, Misrepair mechanism is also important in biological adaptation. Misrepair is a strategy of repair for increasing the surviving chance of an organism when it suffers from severe injuries. As a surviving strategy, Misrepair mechanism plays also an important role in individual adaptation, species survival, and species differentiation. Firstly, Misrepair of an injury is one of the manners of individual adaptation; and Misrepair mechanism gives an organism a great potential in adapting to changeable and destructive environment. Secondly, Misrepair mechanism is important in maintaining and enlarging the diversity of genome DNAs of a species; and a large diversity of genome DNAs is essential for the adaptation and the differentiation of a species in different environments. On one hand, somatic Misrepairs are essential for maintaining the sufficient number of individuals in a species, which are the vectors of different genome DNAs. On the other hand, Misrepair of DNA is a source of DNA mutations and the DNA Misrepairs in germ cells may contribute to the diversity of genome DNAs in a species. In conclusion, Misrepair mechanism is a mechanism essential for individual adaptation, species adaptation, and species evolution.