Has wild poliovirus been eliminated from Nigeria?
Michael Famulare

TL;DR
This study uses a transmission model to estimate the likelihood of poliovirus elimination in Nigeria and globally, finding high probabilities of WPV1 and WPV3 eradication but ongoing cVDPV2 transmission as of 2015.
Contribution
It provides a probabilistic assessment of poliovirus elimination in Nigeria using a transmission model accounting for detection uncertainties.
Findings
Probability of WPV1 elimination in Nigeria is 84%.
WPV3 eradication probability exceeds 99%.
Ongoing cVDPV2 transmission is likely, with an 83% chance of elimination if no new cases occur by April 2016.
Abstract
Wild poliovirus type 3 (WPV3) has not been seen anywhere since the last case of WPV3-associated paralysis in Nigeria in November 2012. At the time of writing, the most recent case of wild poliovirus type 1 (WPV1) in Nigeria occurred in July 2014, and WPV1 has not been seen in Africa since a case in Somalia in August 2014. No cases associated with circulating vaccine-derived type 2 poliovirus (cVDPV2) have been detected in Nigeria since November 2014. Has WPV1 been eliminated from Africa? Has WPV3 been eradicated globally? Has Nigeria interrupted cVDPV2 transmission? These questions are difficult because polio surveillance is based on paralysis and paralysis only occurs in a small fraction of infections. This report provides estimates for the probabilities of poliovirus elimination in Nigeria given available data as of March 31, 2015. It is based on a model of disease transmission that…
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