The Simulation Powers and Limitations of Higher Temperature Hierarchical Self-Assembly Systems
Jacob Hendricks, Matthew J. Patitz, Trent A. Rogers

TL;DR
This paper investigates the simulation capabilities of hierarchical self-assembly systems in the 2-Handed Assembly Model at different temperatures, revealing fundamental limits and distinctions between simulation types.
Contribution
It characterizes when higher temperature systems can simulate lower temperature ones and proves the first impossibility result for downward simulation in temperature hierarchies.
Findings
Higher temperature systems can intrinsically universalize certain lower temperature systems.
Strong and standard simulation definitions are not equivalent, with the latter being more permissive.
First impossibility result established for downward simulation in temperature hierarchies.
Abstract
In this paper, we extend existing results about simulation and intrinsic universality in a model of tile-based self-assembly. Namely, we work within the 2-Handed Assembly Model (2HAM), which is a model of self-assembly in which assemblies are formed by square tiles that are allowed to combine, using glues along their edges, individually or as pairs of arbitrarily large assemblies in a hierarchical manner, and we explore the abilities of these systems to simulate each other when the simulating systems have a higher "temperature" parameter, which is a system wide threshold dictating how many glue bonds must be formed between two assemblies to allow them to combine. It has previously been shown that systems with lower temperatures cannot simulate arbitrary systems with higher temperatures, and also that systems at some higher temperatures can simulate those at particular lower…
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