Study on Microdosimetric Characteristics of 120MeV/u to 430MeV/u Carbon Ions

TL;DR

This study uses Monte Carlo simulations to analyze microdosimetric spectra of carbon ions across a range of energies, aiding in improved treatment planning for carbon ion radiotherapy.

Contribution

It provides a detailed simulation and comparison of microdosimetric spectra for carbon ions from 120MeV/u to 430MeV/u, enhancing understanding for radiotherapy applications.

Findings

Simulated energy deposition patterns match experimental data.

Calculated spectra and energy values inform treatment planning.

Results support the use of microdosimetric analysis in radiotherapy.

Abstract

Microdosimetric single event spectra is a significant parameter in radiotherapy, which can be used to evaluate the biological effect of radiation fields. This paper simulated microscopic patterns of energy depositions for mixed radiation fields which are created by carbon ions with general purpose Monte Carlo code FLUKA. . Experimental measured lineal energy spectra produced by carbon ions of about 300MeV/u were chosen from literature to compared with the results from simulation one of the measurement set-up. In addition, the dose-weighted lineal energy spectra, frequency averaged lineal energy values and dose averaged lineal energy values of carbon ions from 120MeV/u to 430MeV/u of the measurement set-up were calculated, too. The results of this paper are meaningful for making treatment planning in carbon ion radiotherapy.