Characterization studies of Silicon Photomultipliers and crystals matrices for a novel time of flight PET detector

TL;DR

This study characterizes silicon photomultiplier arrays and crystal matrices for a novel PET detector aimed at high-resolution imaging for prostate and pancreatic tumor detection, achieving near 200 ps time resolution.

Contribution

It provides detailed characterization of SiPMs and crystal matrices for a new PET detector, demonstrating performance metrics suitable for high-resolution medical imaging.

Findings

Achieved a Coincidence Time Resolution close to 200 ps FWHM.

Measured an average energy resolution of about 13% at 511 keV.

Evaluated light yield with an average of 1800 pixels fired per interaction.

Abstract

This paper describes the characterization of crystal matrices and silicon photomultiplier arrays for a novel Positron Emission Tomography (PET) detector, namely the external plate of the EndoTOFPET-US system. The EndoTOFPET-US collaboration aims to integrate Time-Of-Flight PET with ultrasound endoscopy in a novel multimodal device, capable to support the development of new biomarkers for prostate and pancreatic tumors. The detector consists in two parts: a PET head mounted on an ultrasound probe and an external PET plate. The challenging goal of 1 mm spatial resolution for the PET image requires a detector with small crystal size, and therefore high channel density: 4096 LYSO crystals individually readout by Silicon Photomultipliers (SiPM) make up the external plate. The quality and properties of these components must be assessed before the assembly. The dark count rate, gain, breakdown voltage and correlated noise of the SiPMs are measured, while the LYSO crystals are evaluated in terms of light yield and energy resolution. In order to effectively reduce the noise in the PET image, high time resolution for the gamma detection is mandatory. The Coincidence Time Resolution (CTR) of all the SiPMs assembled with crystals is measured, and results show a value close to the demanding goal of 200 ps FWHM. The light output is evaluated for every channel for a preliminary detector calibration, showing an average of about 1800 pixels fired on the SiPM for a 511 keV interaction. Finally, the average energy resolution at 511 keV is about 13 %, enough for effective Compton rejection.