Response-adaptive randomization: an overview of designs and asymptotic theory

TL;DR

This paper reviews key research on response-adaptive randomization, highlighting its design strategies and asymptotic properties, to inform future clinical trial methodologies.

Contribution

It offers a comprehensive overview of response-adaptive randomization designs and their asymptotic theoretical foundations, summarizing decades of research.

Findings

Summarizes major response-adaptive randomization designs

Highlights asymptotic properties of these designs

Provides insights for future clinical trial methods

Abstract

In this paper we provide an overview of important research works on response-adaptive randomization completed in the past decades.