Single Channel Cutaneous Electrogastrography Parameters from Local White Rabbit (Oryctolagus cuniculus)

TL;DR

This study analyzes various electrogastrography parameters in rabbits, revealing that parameters beyond the commonly used dominant frequency and cycle per minute provide significant diagnostic information.

Contribution

It demonstrates that EGG parameterization should include voltage and amplitude measures, not just frequency-based parameters, challenging traditional diagnostic practices.

Findings

No significant difference in dominant frequency and cpm among datasets.

Significant differences found in voltage and amplitude parameters.

Suggests expanding EGG analysis beyond frequency parameters.

Abstract

EGG recordings performed on 13 local white rabbits (O. cuniculus) which divided into 3 groups; acetosal 35 mg/kgBM receiver, reserpine 37.5 mg/kgBM receiver, and control group. A total of 72 EGG recordings obtained from them, which divided furthermore into 9 datasets based on prepandrial state, postpandrial state, and post 1 hour drug administration state. EGG parameters such as the number of cycle per minute ($cpm$), average voltage of action potential segment ($\bar{V_a}$), root mean square voltage of action potential segment ($A_{rms}$), root mean square voltage of all EGG segment ($V_{rms}$), average period of action potential segment ($\bar{T_a}$), average period of resting plateau ($\bar{T_i}$), average period difference among action potential segment and resting plateau ($\bar{T_a - T_i}$), and dominant frequency ($f_d$) are obtained. Insignificant difference of $f_d$ ($P$ = 0.9112993) and cpm ($P$ = 0.9382463) among 9 EGG datasets were found. These findings contrasted the common practice of EGG assessment, which $f_d$ and $cpm$ are the main parameters for diagnosis base. In other hand, significant difference between 9 EGG datasets found for $\bar{V_a}$, $A_{rms}$, and $V_{rms}$ parameter with $P$ = 0.0007346, 0.0039191, and 0.0000559 respectively. In conclusion, EGG parameterization should not be limited to $f_d$ and $cpm$ only.