A topological framework for signed permutations
Fenix W.D. Huang, Christian M. Reidys

TL;DR
This paper introduces a topological framework using fatgraphs to analyze signed permutations and their reversal distances, providing an alternative interpretation of the Hannenhalli-Pevzner formula.
Contribution
It develops a novel topological approach with $mbda$-maps, simplifying the understanding of reversals without padding and connecting topological genus changes to permutation reversals.
Findings
Reversals act via slicing, gluing, or half-flipping of fatgraph vertices.
Any reversal changes the topological genus by at most one.
The framework offers an alternative derivation of the Hannenhalli-Pevzner formula.
Abstract
In this paper we present a topological framework for studying signed permutations and their reversal distance. As a result we can give an alternative approach and interpretation of the Hannenhalli-Pevzner formula for the reversal distance of signed permutations. Our approach utlizes the Poincar\'e dual, upon which reversals act in a particular way and obsoletes the notion of "padding" of the signed permutations. To this end we construct a bijection between signed permutations and an equivalence class of particular fatgraphs, called -maps, and analyze the action of reversals on the latter. We show that reversals act via either slicing, gluing or half-flipping of external vertices, which implies that any reversal changes the topological genus by at most one. Finally we revisit the Hannenhalli-Pevzner formula employing orientable and non-orientable, irreducible, -maps.
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Taxonomy
TopicsGenome Rearrangement Algorithms · Chromosomal and Genetic Variations
