Chemotactic systems in the presence of conflicts: a new functional inequality

TL;DR

This paper explores a generalized functional inequality related to chemotactic systems with conflicting interactions between two cell populations, extending classical models and inequalities like the Keller-Segel and Moser-Trudinger inequalities.

Contribution

It introduces a new functional inequality that generalizes the Moser-Trudinger inequality for chemotactic systems with conflicting population interactions.

Findings

Identification of a new inequality for conflicting populations

Extension of Keller-Segel model to two populations with opposing interactions

Connection between the inequality and system stability

Abstract

The evolution of a chemotactic system involving a population of cells attracted to self-produced chemicals is described by the Keller-Segel system. In spacial dimension 2, this system demonstrates a balance between the spreading effect of diffusion and the concentration due to self-attraction. As a result, there exists a critical "mass" (i.e. total cell's population) above which the solution of this system collapses in a finite time, while below this critical mass there is global existence in time. The existence of this critical mass is related to a functional inequality known as the Moser-Trudinger inequality. An extension of the Keller-Segel model to several cells populations was considered before in the literature. Here we review some of these results and, in particular, consider the case of conflict between two populations, that is, when population one attracts population two, while, at the same time, population two repels population one. This assumption leads to a new functional inequality which generalizes the Moser-Trudinger inequality.