Optimizing Hybrid Spreading in Metapopulations
Changwang Zhang, Shi Zhou, Joel C. Miller, Ingemar J. Cox, and, Benjamin M. Chain

TL;DR
This paper develops a theoretical framework to analyze hybrid epidemic spreading, revealing critical conditions where combined local and global spreading mechanisms maximize outbreak size.
Contribution
It introduces a novel model for hybrid epidemics and identifies optimal spreading balances, including critically hybrid scenarios that amplify outbreaks.
Findings
Existence of critically hybrid epidemics with large outbreaks
Optimal balance between local and global spreading mechanisms
Strategies for maximizing beneficial and estimating damaging epidemics
Abstract
Epidemic spreading phenomena are ubiquitous in nature and society. Examples include the spreading of diseases, information, and computer viruses. Epidemics can spread by local spreading, where infected nodes can only infect a limited set of direct target nodes and global spreading, where an infected node can infect every other node. In reality, many epidemics spread using a hybrid mixture of both types of spreading. In this study we develop a theoretical framework for studying hybrid epidemics, and examine the optimum balance between spreading mechanisms in terms of achieving the maximum outbreak size. We show the existence of critically hybrid epidemics where neither spreading mechanism alone can cause a noticeable spread but a combination of the two spreading mechanisms would produce an enormous outbreak. Our results provide new strategies for maximising beneficial epidemics and…
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