Two Modeling Strategies for Empirical Bayes Estimation
Bradley Efron

TL;DR
This paper compares two main strategies for empirical Bayes estimation—modeling on the parameter space ($g$-modeling) and the data space ($f$-modeling)—evaluating their accuracy and practical strengths through examples.
Contribution
It provides a detailed comparison of $g$-modeling and $f$-modeling strategies, including new computational formulas for assessing their accuracy.
Findings
Both strategies have specific strengths and limitations.
Computational formulas help evaluate the frequentist accuracy of each approach.
Examples illustrate practical applications and differences of the two methods.
Abstract
Empirical Bayes methods use the data from parallel experiments, for instance, observations for , to estimate the conditional distributions . There are two main estimation strategies: modeling on the space, called "-modeling" here, and modeling on the space, called "-modeling." The two approaches are described and compared. A series of computational formulas are developed to assess their frequentist accuracy. Several examples, both contrived and genuine, show the strengths and limitations of the two strategies.
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