An Algorithm for Alignment-free Sequence Comparison using Logical Match

TL;DR

This paper introduces an alignment-free DNA sequence comparison algorithm that uses fuzzy logic to score matches and mismatches, demonstrating efficiency and effectiveness on artificial and real data.

Contribution

The paper presents a novel alignment-free sequence comparison method utilizing fuzzy membership values, improving computational time and accuracy over existing approaches.

Findings

Effective comparison of DNA sequences using fuzzy logic

Demonstrated on artificial and real datasets from NCBI

Shows improved computational efficiency

Abstract

This paper proposes an algorithm for alignment-free sequence comparison using Logical Match. Here, we compute the score using fuzzy membership values which generate automatically from the number of matches and mismatches. We demonstrate the method with both the artificial and real datum. The results show the uniqueness of the proposed method by analyzing DNA sequences taken from NCBI databank with a novel computational time.