Activity Modulation of Motor and Somatosensory Neurons in Learning

TL;DR

This study investigates how motor and somatosensory neurons in macaque monkeys' cortex change activity during learning a tongue protrusion task, highlighting differences between successful and failed trials across sessions.

Contribution

It provides new insights into neural activity differences between successful and unsuccessful trials during learning, emphasizing the formation of cell assemblies and session-to-session comparisons.

Findings

Neural responses differ significantly between successful and failed trials.

Cell assemblies develop during the adaptation process.

Differences in activity become more pronounced as learning progresses.

Abstract

The cortical processes involved in learning are not well understood. Recent experiments have studied population-level response in the orofacial somatosensory (S1) and motor (S1) cortices of rhesus macaque monkeys during adaptation to a simple tongue protrusion task within and across multiple learning sessions. Initial findings have suggested the formation of cell assemblies during adaptation. In this report we explore differences in cell activity between successful and failed trials as the monkey learns during two sessions. The ability to directly compare data across multiple sessions is fairly new and until now research has mostly focused on the activity of neurons during successful trials only. We confirm findings of the development of coherently active cell assemblies and find that neural response differentiates significantly between successful and unsuccessful trials, particularly as the monkey adapts to the task. Our findings motivate further research into the differences in activity between successful and unsuccessful trials in these experiments.