Interference of Binding Protein with Serum Growth Hormone Measurements

TL;DR

This paper demonstrates that mass spectrometry can accurately measure serum growth hormone without interference from binding proteins, unlike traditional antibody-based methods.

Contribution

It introduces mass spectrometry as a reliable alternative for serum growth hormone measurement unaffected by binding protein interference.

Findings

Mass spectrometry is unaffected by growth hormone binding protein interference.

Mass spectrometry provides more accurate serum growth hormone measurements.

Traditional antibody-based methods are prone to interference from binding proteins.

Abstract

Measurement of serum growth hormone by mass spectrometry is demonstrated to be unaffected by interferences with growth hormone binding protein as frequently encountered with antibody-based routine test methods and provides an alternative approach, therefore, to acquisition of accurate results.