Mapping neuron positions to curved cortical surfaces

TL;DR

This paper extends cortical slice models to include arbitrary curvatures, enabling investigation of how folding affects neuron density and layer structure in realistic cortical tissue simulations.

Contribution

It introduces a method to incorporate arbitrary curvature into cortical models, advancing the realism of neural tissue simulations.

Findings

Curvature influences neuron density distribution.

Folding affects layer morphology.

Enhanced model allows realistic cortical surface simulation.

Abstract

Real cortical tissue curves and folds according to experimental data. However, our current simulations only use unfolded cortical layers. This project extends the cortical slice model in order to be able to specify arbitrary curvatures to the cortical layers and investigate the effect of curvature and folding on neuron density and layer morphology.