Time-resolved particle image velocimetry measurements with wall shear stress and uncertainty quantification for the FDA benchmark nozzle model

TL;DR

This study validates CFD analyses of medical devices using advanced time-resolved PIV techniques, providing detailed flow measurements, wall shear stress data, and uncertainty quantification for the FDA benchmark nozzle model.

Contribution

It introduces enhanced PIV processing methods and comprehensive uncertainty analysis for flow and shear stress measurements in the FDA benchmark nozzle model.

Findings

Increased spatial resolution improved flow measurement accuracy.

Advanced processing techniques enhanced signal-to-noise ratios.

Uncertainty quantification was successfully integrated into shear stress analysis.

Abstract

We present validation of benchmark experimental data for computational fluid dynamics (CFD) analyses of medical devices using advanced Particle Image Velocimetry (PIV) processing and post-processing techniques. This work is an extension of a previous FDA-sponsored multi-laboratory study, which used a medical device mimicking geometry referred to as the FDA benchmark nozzle model. Time-resolved PIV analysis was performed in five overlapping regions of the model for Reynolds numbers in the nozzle throat of 500, 2,000, 5,000, and 8,000. Images included a two-fold increase in spatial resolution in comparison to the previous study. Data was processed using ensemble correlation, dynamic range enhancement, and phase correlations to increase signal-to-noise ratios and measurement accuracy, and to resolve flow regions with large velocity ranges and gradients, which is typical of many blood-contacting medical devices. Parameters relevant to device safety, including shear stress at the wall and in bulk flow, were computed using radial basis functions (RBF) to improve accuracy. In-field spatially resolved pressure distributions, Reynolds stresses and energy dissipation rates were computed from PIV measurements. Velocity measurement uncertainty was estimated directly from the PIV correlation plane, and uncertainty analysis for wall shear stress at each measurement location was performed using a Monte Carlo model. (truncated abstract)