Markers of criticality in phase synchronisation

TL;DR

This paper introduces a new framework for detecting criticality in neural phase synchronisation, linking it to brain dynamics and resting state properties, supported by models and EEG/EMG data.

Contribution

It proposes a novel metric and methods for identifying LRTCs in phase synchronisation, validated through models and human data, advancing understanding of brain criticality.

Findings

LRTCs in phase synchronisation can be detected in models and human EEG/EMG data.

Resting state brain activity shows evidence of LRTCs, indicating non-local behaviour.

LRTCs may reflect a readiness state for rapid neural state shifts.

Abstract

The concept of the brain as a critical system is very attractive because systems close to criticality are thought to maximise their dynamic range of information processing and communication. To date, there have been two key experimental observations supporting this hypothesis: i) neuronal avalanches with power law distribution of size and ii) long-range temporal correlations (LRTCs) in the amplitude of neural oscillations. The case for how these maximise dynamic range of information processing and communication is still being made and because a significant substrate for information coding and transmission is neural synchrony it is of interest to link synchronisation measures with those of criticality. We propose a framework for characterising criticality in synchronisation based on a new metric of phase synchronisation (rate of change of phase difference) and a set of methods we have developed for detecting LRTCs. We test this framework against two classical models of criticality (Ising and Kuramoto) and recently described variants of these models aimed to more closely represent human brain dynamics. From these simulations we determine the parameters at which these systems show evidence of LRTCs in phase synchronisation. We demonstrate proof of principle by analysing pairs of human simultaneous EEG and EMG time series, suggesting that LRTCs of corticomuscular phase synchronisation can be detected in the resting state. The existence of LRTCs in fluctuations of phase synchronisation suggests that these fluctuations are governed by non-local behaviour. This has important implications regarding the conditions under which one should expect to see LRTCs in phase synchronisation. Specifically, brain resting states may exhibit LRTCs reflecting a state of readiness facilitating rapid task-dependent shifts towards and away from synchronous states that abolish LRTCs.