FPCB : a simple and swift strategy for mirror repeat identification

TL;DR

The paper introduces FPCB, a simple and fast method for identifying mirror repeats in DNA sequences, which could aid in understanding their functional roles in genetics and evolution.

Contribution

A novel, straightforward three-step strategy (FPCB) for rapid detection of mirror repeats in nucleotide sequences.

Findings

Analyzed at least twenty genes using FPCB.

Identified various types of mirror repeats and proposed nomenclature.

Demonstrated the method's potential in functional and evolutionary studies.

Abstract

After the recent advancement of sequencing strategies, mirror repeats have been found to be present in the gene sequence of many organisms and species. This presence of mirror repeats in most of the sequences indicates towards some important functional role of these repeats. However, a simple and quick strategy to search these repeats in a given sequence is not available. We in this manuscript have proposed a simple and swift strategy named as FPCB strategy to identify mirror repeats in a give sequence. The strategy includes three simple steps of downloading sequencing in FASTA format (F), making its parallel complement (PC) and finally performing a homology search with the original sequence (B). At least twenty genes were analyzed using the proposed study. A number and types of mirror repeats were observed. We have also tried to give nomenclature to these repeats. We hope that the proposed FPCB strategy will be quite helpful for the identification of mirror repeats in DNA or mRNA sequence. Also the strategy may help in unraveling the functional role of mirror repeats in various processes including evolution.