Zen and the Science of Pattern Identification: An Inquiry into Bayesian Skepticism
Deborah A. Striegel, Damian Wojtowicz, Teresa M. Przytycka, Vipul, Periwal

TL;DR
This paper introduces a novel quantum field theory-inspired approach to exactly identify data patterns, enabling rapid analysis of complex datasets like images and protein sequences without prior assumptions.
Contribution
It redefines Bayesian inference using quantum field theory methods to efficiently find pattern landscapes in large, complex datasets.
Findings
Exact pattern landscapes can be computed in minutes on standard computers.
The method applies to diverse data types, including images and protein sequences.
No prior model assumptions are needed for pattern detection.
Abstract
Finding patterns in data is one of the most challenging open questions in information science. The number of possible relationships scales combinatorially with the size of the dataset, overwhelming the exponential increase in availability of computational resources. Physical insights have been instrumental in developing efficient computational heuristics. Using quantum field theory methods and rethinking three centuries of Bayesian inference, we formulated the problem in terms of finding landscapes of patterns and solved this problem exactly. The generality of our calculus is illustrated by applying it to handwritten digit images and to finding structural features in proteins from sequence alignments without any presumptions about model priors suited to specific datasets. Landscapes of patterns can be uncovered on a desktop computer in minutes.
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Taxonomy
TopicsGenetics, Bioinformatics, and Biomedical Research · Fractal and DNA sequence analysis · Data Visualization and Analytics
