Influence of Tissue Geometry on Transversal Relaxation

TL;DR

This paper investigates how tissue geometry influences transverse relaxation in NMR, using numerical solutions of the Bloch-Torrey Equation to explore the potential for deducing microscopic tissue structures from relaxation data.

Contribution

It introduces a Monte Carlo simulation approach to analyze the impact of tissue geometry and off-resonance fields on transverse relaxation in NMR.

Findings

Off-resonance fields significantly affect relaxation rates.

Simulation results suggest possible tissue geometry inference from relaxation data.

Monte Carlo approach effectively models microscopic tissue effects.

Abstract

With today's NMR techniques some microscopic geometry of tissue can still not be resolved directly. Often, there is also a specific off resonance field related to this geometry. In this work the impact of these off resonances on the transverse relaxation is investigated. Therefore the Bloch-Torrey Equation was numerically solved with a Monte Carlo approach, and the feasibility to deduce information about the geometry of the tissue from the simulated transverse magnetization rates was analysed.