Comment on "Steady-state fluctuations of a genetic feedback loop: an exact solution" [J. Chem. Phys. {\bf 137}, 035104 (2012).]
Guilherme C.P. Innocentini, Alexandre F. Ramos, Jos\'e Eduardo M., Hornos
TL;DR
This paper responds to criticisms of a previous exact solution for genetic feedback loop fluctuations, providing missing components to complete the analytic model.
Contribution
It offers a detailed reply and completes the analytic solution for the genetic feedback loop model discussed in the original paper.
Findings
Clarifies the criticisms and addresses them with additional analysis.
Completes the analytic solution to the genetic feedback loop model.
Strengthens the validity of the original model's conclusions.
Abstract
The comment is intended to answer the criticism presented on `Steady-state fluctuations of a genetic feedback loop: an exact solution' [J. Chem. Phys. {\bf 137}, 035104 (2012).] and provides the missing component for the complete analytic solutions to the author's model.
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Taxonomy
TopicsGene Regulatory Network Analysis · Evolution and Genetic Dynamics · Photosynthetic Processes and Mechanisms