Graphene transistors for bioelectronics

TL;DR

This paper reviews graphene solution-gated transistors, discussing their fabrication, interface properties, biocompatibility, and application in recording electrical activity of electrogenic cells for bioelectronics.

Contribution

It provides a comprehensive overview of graphene SGFETs, including fabrication, interface understanding, biocompatibility, and experimental validation in bioelectronic applications.

Findings

Graphene SGFETs can effectively record electrical activity of electrogenic cells.

Graphene shows good biocompatibility with primary neuron cultures.

The detailed interface analysis enhances understanding of solution-gated transistor operation.

Abstract

This paper provides an overview on graphene solution-gated field effect transistors (SGFETs) and their applications in bioelectronics. The fabrication and characterization of arrays of graphene SGFETs is presented and discussed with respect to competing technologies. To obtain a better understanding of the working principle of solution-gated transistors, the graphene-electrolyte interface is discussed in detail. The in-vitro biocompatibility of graphene is assessed by primary neuron cultures. Finally, bioelectronic experiments with electrogenic cells are presented, confirming the suitability of graphene to record the electrical activity of cells.