Environmental Influence on Dental Morphology

TL;DR

This study investigates how environmental stressors, such as malnutrition and disease, influence the morphological variation of human upper molars, revealing increased variability and specific trait changes in stressed individuals.

Contribution

It provides the first evidence that environmental stress significantly affects dental morphology, supporting the morphodynamic model of dental development.

Findings

Stress increases morphological variability in molars.

Stressed individuals show larger and more numerous cusps.

Environmental factors influence dental developmental outcomes.

Abstract

Development is a complex phenomenon where the forming phenotype interacts with genetic and environmental inputs. Teeth are an important model for developmental studies and their development has been thoroughly investigated. However, despite of a large literature on the genetics of dental development, no studies have focused yet on the environmental influences on dental morphology. Here, we aim to test whether and to what extent the environment plays a role in producing morphological variation in human teeth. We selected a sample of modern human skulls and we used dental enamel hypoplasia as an environmental stress marker in order to identify two groups with different stress level, referred to as SG ("stressed" group) and NSG ("non-stressed" group). We collected data on the occurrence and the relative development of 15 morphological traits (5 for each molar) on upper molars using a standard methodology commonly used in dental anthropology (ASU-DAS system) and then we compared the frequencies of the traits in the two groups. Overall, the results suggest that: (i) stressors like malnutrition and/or systemic diseases have a significant effect on upper molar morphology; (ii) stress generates a developmental response which increases the morphological variability of the SG; (iii) the increase of variability is directional, since individuals belonging to the SG have increased cusps dimensions and number. These results are consistent with the expectations of the morphodynamic model of dental development (Jernvall, 1995).