Anatomical MRI with an atomic magnetometer

TL;DR

This paper demonstrates for the first time that atomic magnetometers can be used for anatomical MRI at 85 kHz, achieving resolutions comparable to traditional methods without cryogenics, potentially enabling portable and cost-effective medical imaging.

Contribution

It introduces the novel application of atomic magnetometers for anatomical MRI at 85 kHz, overcoming previous sensitivity and noise challenges associated with low-frequency operation.

Findings

Achieved 1.1x1.4 mm² resolution in 6 minutes with SNR of 10.

First demonstration of atomic magnetometers for anatomical MRI.

Potential to improve sensitivity to 1x1 mm² resolution.

Abstract

Ultra-low field (ULF) MRI is a promising method for inexpensive medical imaging with various additional advantages over conventional instruments such as low weight, low power, portability, absence of artifacts from metals, and high contrast. Anatomical ULF MRI has been successfully implemented with SQUIDs, but SQUIDs have the drawback of cryogen requirement. Atomic magnetometers have sensitivity comparable to SQUIDs and can be in principle used for ULF MRI to replace SQUIDs. Unfortunately some problems exist due to the sensitivity of atomic magnetometers to magnetic field and gradients. At low frequency, noise is also substantial and a shielded room is needed for improving sensitivity. In this paper, we show that at 85 kHz, the atomic magnetometer can be used to obtain anatomical images. This is the first demonstration of any use of atomic magnetometers for anatomical MRI. The demonstrated resolution is 1.1x1.4 mm2 in about six minutes of acquisition with SNR of 10. Some applications of the method are discussed. With several measures it is also possible to increase sensitivity to reach resolution 1x1 mm2, which is typical in medical imaging.