Unfolding Large Biomolecules

TL;DR

This paper proposes a novel method to study the conformational dynamics of large biomolecules by trapping their ions in a Paul trap, enabling detailed investigation of their behavior and interactions with solvent environments.

Contribution

It introduces a new experimental approach for analyzing large biomolecular ions using ion trapping techniques, which has not been extensively explored before.

Findings

Demonstrated trapping of large biomolecular ions

Potential to observe conformational changes in real-time

Provides insights into biomolecular-solvent interactions

Abstract

The conformational dynamics of biomolecules drives the chemistry of life. We propose trapping large biomolecular ions in a Paul trap to probe their dynamics and that of their surrounding solvent cage.