Projected Subgradient Methods for Learning Sparse Gaussians
John Duchi, Stephen Gould, Daphne Koller

TL;DR
This paper introduces a novel projected subgradient method for efficiently learning sparse Gaussian Markov random fields, with extensions to block sparsification, demonstrating improved performance in biological and image analysis tasks.
Contribution
It presents a new projected gradient approach for sparse GMRF learning, including block sparsification, outperforming previous methods in speed and generalization.
Findings
Faster practical convergence than previous methods
Effective block sparsification with better generalization
Successful application to biological and image data
Abstract
Gaussian Markov random fields (GMRFs) are useful in a broad range of applications. In this paper we tackle the problem of learning a sparse GMRF in a high-dimensional space. Our approach uses the l1-norm as a regularization on the inverse covariance matrix. We utilize a novel projected gradient method, which is faster than previous methods in practice and equal to the best performing of these in asymptotic complexity. We also extend the l1-regularized objective to the problem of sparsifying entire blocks within the inverse covariance matrix. Our methods generalize fairly easily to this case, while other methods do not. We demonstrate that our extensions give better generalization performance on two real domains--biological network analysis and a 2D-shape modeling image task.
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Taxonomy
TopicsGene expression and cancer classification · Gaussian Processes and Bayesian Inference · Cell Image Analysis Techniques
