Global minimizers for axisymmetric multiphase membranes
Rustum Choksi, Marco Morandotti, Marco Veneroni

TL;DR
This paper studies the shape optimization of axisymmetric multiphase biomembranes by minimizing a phase-dependent Canham-Helfrich energy combined with line tension, proving the existence of global minimizers.
Contribution
It extends previous work to multiphase membranes with phase-dependent energies and establishes the existence of global minimizers in the axisymmetric setting.
Findings
Existence of global minimizers for the multiphase membrane problem.
Extension of previous single-phase results to multiphase cases.
Framework for analyzing phase-dependent membrane shapes.
Abstract
We consider a Canham-Helfrich-type variational problem defined over closed surfaces enclosing a fixed volume and having fixed surface area. The problem models the shape of multiphase biomembranes. It consists of minimizing the sum of the Canham-Helfrich energy, in which the bending rigidities and spontaneous curvatures are now phase-dependent, and a line tension penalization for the phase interfaces. By restricting attention to axisymmetric surfaces and phase distributions, we extend our previous results for a single phase (arXiv:1202.1979) and prove existence of a global minimizer.
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Taxonomy
TopicsCell Adhesion Molecules Research · Cellular Mechanics and Interactions · Phagocytosis and Immune Regulation
