GC3 Biology in Eukaryotes and Prokaryotes
Eran Elhaik, Tatiana Tatarinova

TL;DR
This paper explores the distribution and evolutionary trends of GC content at the third codon position across various species, providing a unified view of GC3 biology in both eukaryotes and prokaryotes.
Contribution
It offers a comprehensive analysis of GC3 distribution, compares evolutionary patterns, and integrates existing theories into a unified framework for understanding GC3 biology.
Findings
GC3 content varies significantly among species
Distinct evolutionary trends observed in GC3 levels
Differences between gene and organism GC3 distributions
Abstract
We describe the distribution of Guanine and Cytosine (GC) content in the third codon position (GC3) distributions in different species, analyze evolutionary trends and discuss differences between genes and organisms with distinct GC3 levels. We scrutinize previously published theoretical frameworks and construct a unified view of GC3 biology in eukaryotes and prokaryotes.
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Taxonomy
TopicsRNA and protein synthesis mechanisms · Genomics and Phylogenetic Studies · Bacterial Genetics and Biotechnology
