The Complexity of Synaptic Transmission Revealed by a Multiscale Analysis Approach From The Molecular to The Cellular Level

TL;DR

This paper presents a multiscale analysis approach to understand synaptic transmission, combining molecular and cellular insights with physical and mathematical foundations to quantify stochastic processes involved.

Contribution

It introduces a comprehensive physical and mathematical framework for analyzing the stochastic steps in synaptic transmission across multiple scales.

Findings

Quantification of stochastic steps in synaptic transmission

Development of a multiscale analysis framework

Insights into molecular to cellular level processes

Abstract

Synaptic Transmission is a multiscale process, revealed by various approaches, going from the molecular to the cellular level. This correspondence points out to our recent contributions in this field. We now provide the physical and mathematical foundation, leading to the rational quantification of the analysis of the stochastic steps, underlying synaptic transmission.