Dinamics of HPV Infection among Women with Cervical Lesions

TL;DR

This study investigates the prevalence and persistence of HPV types among women with cervical lesions, highlighting the dominant HPV 16 and the impact of treatment on infection rates.

Contribution

It provides detailed data on HPV type distribution and infection persistence in women with cervical lesions, emphasizing treatment effectiveness.

Findings

HPV 16 had the highest incidence rate at 45%.

Persistent infection was found in 35.7% of initially HPV-positive cases.

Treatment reduced HPV-positive cases from 95% to 35%.

Abstract

A total of 293 women treated at Tomsk Cancer Research Institute were examined. HPV type 16 had the highest incidence rate (45.0%) followed by HPV 31-17,0%, HPV 56/33-15,0%, HPV 51/18/52-13,0%, HPV 58/35/39/45-7,0%, HPV 59-5,0%. Persistent infection was detected in 35.7% of primarily HPV-positive cases (10 out of 28 patients), mainly in cervical cancer patients. Total number of primarily HPV-positive and HPV-negative patients with cervical cancer was 95.0% and 5.0%, respectively. The corresponding values after the complex treatment were 35.0% and 65.0%, respectively, pointing to the treatment efficiency.