On inconsistencies in passive pharmacokinetics
Slawomir Piekarski, Miroslaw Rewekant
TL;DR
This paper investigates inconsistencies in passive pharmacokinetics, suggesting they may stem from inadequate evolution equations, and illustrates this with a one-compartment model example.
Contribution
It highlights the potential role of proper evolution equations in resolving pharmacokinetic inconsistencies, providing a specific example with a one-compartment model.
Findings
Inconsistencies may be due to evolution equation issues
Proper modeling can address pharmacokinetic discrepancies
Illustration with a one-compartment model
Abstract
Some inconsistencies in the passive pharmacokinetics has been observed many years ago. It is possible these inconsistencies result from the lack of proper evolution equations. In this communication, this possibility is illustrated on the example of an evolution equation for an one compartment model.
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Taxonomy
TopicsAnalytical Chemistry and Chromatography · Molecular spectroscopy and chirality · Gene Regulatory Network Analysis