Chemotaxis: from kinetic equations to aggregate dynamics
Fran\c{c}ois James (MAPMO), Nicolas Vauchelet (LJLL, INRIA, Rocquencourt)

TL;DR
This paper derives a nonlocal conservation law from a kinetic chemotaxis model, analyzing measure-valued solutions, blow-up phenomena, and aggregate dynamics, and introduces a numerical scheme for simulation.
Contribution
It develops a rigorous framework for the hydrodynamic limit of chemotaxis models, including existence, uniqueness, and numerical methods for measure-valued solutions.
Findings
Finite time blow-up leads to measure-valued solutions.
Existence of solutions via duality methods.
Numerical scheme based on particle methods.
Abstract
The hydrodynamic limit for a kinetic model of chemotaxis is investigated. The limit equation is a non local conservation law, for which finite time blow-up occurs, giving rise to measure-valued solutions and discontinuous velocities. An adaptation of the notion of duality solutions, introduced for linear equations with discontinuous coefficients, leads to an existence result. Uniqueness is obtained through a precise definition of the nonlinear flux as well as the complete dynamics of aggregates, i.e. combinations of Dirac masses. Finally a particle method is used to build an adapted numerical scheme.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsMathematical Biology Tumor Growth · Cellular Mechanics and Interactions · Microtubule and mitosis dynamics
