Residual Component Analysis
Alfredo A. Kalaitzis, Neil D. Lawrence

TL;DR
Residual Component Analysis (RCA) extends probabilistic PCA to decompose residual variance after accounting for known factors, unifying and generalizing methods like CCA, with applications in gene expression and pose recovery.
Contribution
The paper introduces Residual Component Analysis (RCA), a novel framework that generalizes PCA and CCA to analyze residual variance in data.
Findings
RCA unifies PCA and CCA as special cases.
Demonstrated RCA on gene expression time series data.
Applied RCA to human pose recovery from silhouettes.
Abstract
Probabilistic principal component analysis (PPCA) seeks a low dimensional representation of a data set in the presence of independent spherical Gaussian noise, Sigma = (sigma^2)*I. The maximum likelihood solution for the model is an eigenvalue problem on the sample covariance matrix. In this paper we consider the situation where the data variance is already partially explained by other factors, e.g. covariates of interest, or temporal correlations leaving some residual variance. We decompose the residual variance into its components through a generalized eigenvalue problem, which we call residual component analysis (RCA). We show that canonical covariates analysis (CCA) is a special case of our algorithm and explore a range of new algorithms that arise from the framework. We illustrate the ideas on a gene expression time series data set and the recovery of human pose from silhouette.
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Taxonomy
TopicsGene expression and cancer classification · Spectroscopy and Chemometric Analyses · Fractal and DNA sequence analysis
