Effects of noise on models of spiny dendrites

TL;DR

This study examines how different types of noise affect wave propagation in two models of spiny dendrites, revealing that noise influences wave speed differently depending on the model and highlighting the robustness of dendritic cables.

Contribution

It introduces an analysis of noise effects on spiny dendrite models, comparing how noise alters wave dynamics and identifying the role of spine density and noise interpretation.

Findings

Wave speed decreases in SDS model with noise

Wave speed increases in BR model with noise

Cable robustness to noise with minimal speed change

Abstract

We study the effects of noise in two models of spiny dendrites. Through the introduction of different types of noise to both the Spike-diffuse-spike (SDS) and Baer-Rinzel (BR) models we investigate the change in behaviour of the travelling wave solutions present in the deterministic systems, as noise intensity increases. We show that the speed of wave propagation in the SDS and BR models respectively decreases and increases as the noise intensity in the spine heads increases. Interestingly the discrepancy between the models does not seem to arise from the type of active spine head dynamics employed by the model but rather by the form of the spine density used. In contrast the cable is very robust to noise and as such the speed shows very little variation from the deterministic system. We look at the effect of the noise interpretation used to evaluate the stochastic integral; Ito or Statonovich and discuss which may be appropriate. We also show that the correlation time and length scales of the noise can enhance propagation of travelling wave solutions where the white noise dominates the signal and produces noise induced phenomena.