The thermodynamic properties of Davydov-Scott's protein model in thermal bath

TL;DR

This paper studies the thermodynamic behavior of the Davydov-Scott protein model in a thermal environment using Lindblad formalism, revealing environmental effects reduce specific heat and strong interactions destabilize the monomer.

Contribution

It applies Lindblad open quantum system formalism to analyze the thermodynamics of the Davydov-Scott model in a thermal bath for the first time.

Findings

Environmental effects decrease specific heat.

Strong amide-I and amide-site interactions destabilize the monomer.

Lindblad formalism effectively models protein thermodynamics.

Abstract

The thermodynamic properties of Davydov-Scott monomer contacting with thermal bath is investigated using Lindblad open quantum system formalism. The Lindblad equation is investigated through path integral method. It is found that the environmental effects contribute destructively to the specific heat, and large interaction between amide-I and amide-site is not preferred for a stable Davydov-Scott monomer.