Introduction to the Special Issue: Genome-Wide Association Studies
Gang Zheng, Jonathan Marchini, Nancy L. Geller
TL;DR
This special issue introduces Genome-Wide Association Studies (GWAS), highlighting their importance in identifying genetic variants linked to complex traits and diseases across the genome.
Contribution
It provides an overview of GWAS methodologies, challenges, and recent advances, serving as a comprehensive introduction for researchers in genetics.
Findings
GWAS has identified numerous genetic loci associated with complex traits.
Advances in statistical methods improve detection power.
Challenges include population stratification and multiple testing.
Abstract
Introduction to the Special Issue: Genome-Wide Association Studies
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