A fibered interference scanning optical microscope for living cell imaging

TL;DR

This paper introduces a fibered interferometric scanning optical microscope capable of high-resolution, 3D imaging of living cells in liquids, offering a fast and cost-effective alternative to traditional microscopy methods.

Contribution

The paper presents a novel fibered interferometric microscope that enables rapid, high-resolution 3D imaging of living cells without complex alignment or expensive equipment.

Findings

Clear visualization of cell topography and surface structures

Effective imaging of living neurons and fibroblasts in liquids

Simplified setup enabling quick sample observation

Abstract

We report on the 3-dimensional imaging of biological cells including living neurons by a recently developed fibered interferometric Scanning Optical Microscope. The topography and surface structure of mouse fibroblasts and hippocampal neurons are clearly revealed. This straightforward technique allows fast, high resolution observation of samples in liquids without lengthy alignment procedures or costly components.