Pore-polymer interaction reveals non-universality in forced polymer translocation

TL;DR

This study demonstrates that the characteristics of forced polymer translocation are highly sensitive to pore model details, challenging the notion of universal scaling laws and highlighting the importance of pore-polymer interactions in out-of-equilibrium dynamics.

Contribution

It reveals that variations in pore models significantly influence translocation behavior, emphasizing the non-universality and complexity of biopolymer translocation under force.

Findings

Pore model variations affect translocation characteristics.

Scaling relations depend on pore model details.

Out-of-equilibrium dynamics are crucial in translocation studies.

Abstract

We present a numerical study of forced polymer translocation by using two separate pore models. Both of them have been extensively used in previous forced translocation studies. We show that variations in the pore model affect the forced translocation characteristics significantly in the biologically relevant pore force, i.e. driving force, range. Details of the model are shown to change even the obtained scaling relations, which is a strong indication of strongly out-of-equilibrium dynamics in the computational studies which have not yet succeeded in addressing the characteristics of the forced translocation for biopolymers at realistic length scale.