TL;DR
This paper demonstrates that DNA nucleotide sequences exhibit cluster-scaling properties similar to turbulent processes, which can enhance models of DNA dynamics by considering these properties in the analysis of specific genes.
Contribution
It introduces the discovery of cluster-scaling properties in DNA sequences and shows how incorporating these properties improves DNA dynamic models.
Findings
DNA sequences have cluster-scaling properties
Cluster-scaling influences hydrogen bonds and stacking interactions
Improved models for DNA dynamics using cluster-scaling
Abstract
It is shown that the nucleotide sequences in DNA molecules have cluster-scaling properties (discovered for the first time in turbulent processes: Sreenivasan and Bershadskii, 2006, J. Stat. Phys., 125, 1141-1153.). These properties are relevant to both types of nucleotide pair-bases interactions: hydrogen bonds and stacking interactions. It is shown that taking into account the cluster-scaling properties can help to improve heterogeneous models of the DNA dynamics. Two human genes: BRCA2 and NRXN1, have been considered as examples.
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