The effect of Immersion medium in optical tweezers

TL;DR

This paper theoretically investigates how the refractive index of immersion oil influences the optimal depth and quality of optical trapping in optical tweezers, providing a numerical method for selecting the best immersion oil for specific samples.

Contribution

It introduces a simple numerical approach to evaluate the impact of immersion oil's refractive index on optical trap performance, aiding in optimal material selection.

Findings

Refractive index affects optimal trap depth and quality.

Numerical method helps in choosing suitable immersion oil.

Guidelines for optimizing optical tweezers setup.

Abstract

In this paper, we report on theoretical investigation of the effect of refractive index of immersion oil on the position of optimal depth and optical trap quality in optical tweezers. Using simple numerical calculation presented here, one can study the optical trapping in different samples, after multi interfaces and find the best choice of immersion oil for a particular case.